Brain Stimulation

Publications on transcranial electrical stimulation (tDCS, tACS, tRNS), modeling, and clinical translation.

All Publications

2026

  • The Rosetta Stone of Neural Mass Models (Physics Reports) · arXiv · Interactive companion site
    Abstract summary: A unifying ladder of neural mass models — from the harmonic and Stuart–Landau oscillators through Wilson–Cowan and Jansen–Rit to the exact mean-field Montbrió–Pazó–Roxin model — written in a single push–pull notation in which stimulation, pharmacology, and coupling all enter as forcing terms on the same underlying oscillator, turning model choice for tES studies into a principled design decision.

  • A whole-brain modeling framework for tDCS montage optimization in drug-resistant epilepsy (medRxiv, September 2026)
    Abstract summary: A neurotwin pipeline for epilepsy tDCS that couples the biophysical head model of the induced field with a personalized whole-brain model of seizure dynamics constrained by structural connectivity and intracranial recordings. In 12 patients the network-informed and field-based optimizations produced different montages despite comparable inhibitory fields at the epileptogenic zone; the differences trace to a few propagation-zone and off-target parcels, often connectome hubs. In six treated patients the predicted spread reduction tracked clinical seizure-frequency change in the expected direction, not significantly; the hypothesis is under prospective test (NCT06334952).

  • From "More Is Different" to Algorithmic Emergence: Regularity, Compression, and the Limits of Discovery (Entropy, accepted October 2026) · Preprints.org · Code and examples
    Abstract summary: Knowing microscopic laws does not guarantee a short description of a retained history, a terminating method that finds one whenever it exists, or a uniformly near-optimal code. Algorithmic emergence is defined through an observer's acquisition of a reusable compressive model, with implementation cost and later coding gains counted.

  • The cortical column as a tuned receiver: a network mechanism for temporal-interference stimulation
    Abstract summary: Temporal-interference (TI) stimulation promises focal, steerable stimulation deep in the brain, where two high-frequency currents overlap and their amplitudes beat at a low difference frequency. Yet an amplitude-modulated field carries no power at that beat frequency, so no passive, linear neuron can follow it. This work resolves the puzzle by modeling the cortical column as a tuned, nonlinear receiver — a network mechanism that demodulates the beat.

  • Persistent infection and chronic neurological disease: reservoirs, CNS seeding, entrenchment, and neural erosion (Zenodo)
    Abstract summary: Organizes infectious contributions to immune-mediated and neurodegenerative disease into one causal sequence (reservoir, seeding, engagement, response, entrenchment, erosion), anchored in reference disorders such as SSPE, PML, neuroHIV, VZV vasculopathy, EBV-associated multiple sclerosis, and post-HSV autoimmune encephalitis, with SARS-CoV-2 as a bridge case. Each less certain branch (HSV-1, HCMV, Chlamydia pneumoniae, periodontal communities, HHV-6/7) must name its reservoir, seeding route, local mediator, entrenchment mechanism, counterevidence, and falsifier.

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  • Realidad y responsabilidad legal
    Abstract summary: Aquesta comunicació pretén plantejar la qüestió de la responsabilitat legal en el context de les noves realitats científiques i en concret respecte de la intel· ligència artificial i la realitat ….

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  • Stationary phase in Coherent State Path Integrals
    Abstract summary: In applying the stationary phase approximation to coherent state path integrals a difficulty occurs; there are no classical paths that satisfy the boundary conditions of the path integral ….

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